Hundreds of years ago, the Chinese Zodiac spirits and their god swore to stay together eternally. United by this promise, the possessed members of the Souma family shall always return to each other under any circumstances. Yet, when these bonds shackle them from freedom, it becomes an undesirable burden—a curse. As head of the clan, Akito is convinced that he shares a special connection with the other Soumas. While he desperately clings to this fantasy, the rest of the family remains isolated and suppressed by the fear of punishment. Tooru Honda, who has grown attached to the Soumas, is determined to break the chains that bind them. Her companionship with the family and her friends encourages her to move forward with lifting the curse. However, due to confounding revelations, she struggles to find the tenacity to continue her endeavors. With time slowly withering away, Tooru contends with an uncertain future in hopes of reaching the tranquility that may lie beyond all this commotion. [Written by MAL Rewrite]

High school student Wakana Gojou spends his days perfecting the art of making hina dolls, hoping to eventually reach his grandfather's level of expertise. While his fellow teenagers busy themselves with pop culture, Gojou finds bliss in sewing clothes for his dolls. Nonetheless, he goes to great lengths to keep his unique hobby a secret, as he believes that he would be ridiculed were it revealed. Enter Marin Kitagawa, an extraordinarily pretty girl whose confidence and poise are in stark contrast to Gojou's meekness. It would defy common sense for the friendless Gojou to mix with the likes of Kitagawa, who is always surrounded by her peers. However, the unimaginable happens when Kitagawa discovers Gojou's prowess with a sewing machine and brightly confesses to him about her own hobby: cosplay. Because her sewing skills are pitiable, she decides to enlist his help. As Gojou and Kitagawa work together on one cosplay outfit after another, they cannot help but grow close—even though their lives are worlds apart. [Written by MAL Rewrite]

Nana Komatsu is a helpless, naïve 20-year-old who easily falls in love and becomes dependent and clingy to those around her. Even though she nurses ambitious dreams of removing herself from her provincial roots and finding her true calling, she ends up traveling to Tokyo with the humble reason of chasing her current boyfriend Shouji Endo. Nana Osaki, on the other hand, is a proud, enigmatic punk rock vocalist from a similarly rural background, who nurtures the desire to become a professional singer. Putting her career with a fairly popular band (and her passionate romance with one of its former members) firmly behind her, she boards the same train to Tokyo as Nana Komatsu. Through a fateful encounter in their journey toward the metropolis, the young women with the same given name are brought together, sparking a chain of events which eventually result in them sharing an apartment. As their friendship deepens, the two attempt to support each other through thick and thin, their deeply intertwined lives filled with romance, music, challenges, and heartbreaks that will ultimately test their seemingly unbreakable bond. [Written by MAL Rewrite]

The rare and inexplicable Puberty Syndrome is thought of as a myth. It is a rare disease which only affects teenagers, and its symptoms are so supernatural that hardly anyone recognizes it as a legitimate occurrence. However, high school student Sakuta Azusagawa knows from personal experience that it is very much real, and happens to be quite prevalent in his school. Mai Sakurajima is a third-year high school student who gained fame in her youth as a child actress, but recently halted her promising career for reasons unknown to the public. With an air of unapproachability, she is well known throughout the school, but none dare interact with her—that is until Sakuta sees her wandering the library in a bunny girl costume. Despite the getup, no one seems to notice her, and after confronting her, he realizes that she is another victim of Puberty Syndrome. As Sakuta tries to help Mai through her predicament, his actions bring him into contact with more girls afflicted with the elusive disease. [Written by MAL Rewrite]